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Acupuncture Research Library

Evidence-based studies and clinical research on acupuncture efficacy

Research StudyChronic Pain

Pressure pain threshold and perceived impact of pain differentially predict short-term and long-term pain reduction following acupuncture in fibromyalgia.

Patients with greater perceived impact of pain at baseline experienced significantly better long-term pain relief with r…

Journal of integrative med…Read More →
Research StudyChronic Pain

Electroacupuncture Modulates Programmed Cell Death 1 Ligand 1 on Peripheral and Central Nervous Systems in a Mouse Fibromyalgia Pain Model.

Electroacupuncture reversed fibromyalgia-induced hyperalgesia by normalizing PD-L1/PD-1 expression in peripheral and cen…

BiomedicinesRead More →
Research StudyChronic Pain

Using Natural Language Processing and Social Media Data to Understand the Lived Experience of People with Fibromyalgia.

Acupuncture was among the three most frequently discussed treatment modalities by fibromyalgia patients on social media,…

Healthcare (Basel, Switzer…Read More →
Research StudyChronic Pain

Electroacupuncture Mitigates TRPV1 Overexpression in the Central Nervous System Associated with Fibromyalgia in Mice.

Electroacupuncture at 2 Hz significantly reduced fibromyalgia-associated mechanical and thermal hypersensitivity by miti…

Life (Basel, Switzerland)Read More →
Case StudyChronic Pain

Early-Phase Intervention With Traditional Japanese Acupuncture and Moxibustion for Fibromyalgia: A Case Report.

Weekly traditional Japanese acupuncture reduced fibromyalgia pain from NRS 6 to 0-2 within six weeks when initiated just…

CureusRead More →
Research StudyChronic Pain

Electroacupuncture Regulates Cannabinoid Receptor 1 Expression in a Mouse Fibromyalgia Model: Pharmacological and Chemogenetic Modulation.

Electroacupuncture significantly reduced fibromyalgia pain in mice by upregulating cannabinoid receptor 1 (CB1) expressi…

Life (Basel, Switzerland)Read More →
Research StudyChronic Pain

Temporal Summation but Not Expectations of Pain Relief Predict Response to Acupuncture Treatment in Fibromyalgia.

Lower baseline temporal summation of pain, but not patient expectations, predicted greater pain relief following electro…

The journal of painRead More →
Research StudyChronic Pain

Electroacupuncture Reduces Fibromyalgia Pain via Neuronal/Microglial Inactivation and Toll-like Receptor 4 in the Mouse Brain: Precise Interpretation of Chemogenetics.

Electroacupuncture significantly reduced fibromyalgia pain in mice by downregulating TLR4 and inflammatory pathways in m…

BiomedicinesRead More →
Meta-AnalysisChronic Pain

Effectiveness of Complementary and Alternative Medicine in Fibromyalgia Syndrome: A Network Meta-Analysis.

Combined acupuncture and massage therapy, along with umbilical needling, demonstrated the greatest efficacy for pain rel…

Journal of pain researchRead More →
Research StudyChronic Pain

Role of ERK in gender difference of fibromyalgia pain.

Male rats demonstrated significantly higher phosphorylated ERK levels in dorsal root ganglia compared to females followi…

Molecular painRead More →
Research StudyChronic Pain

Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse.

Acupoint catgut embedding at ST36 significantly reduced fibromyalgia pain in mice by downregulating TRPV1 signaling path…

Iranian journal of basic m…Read More →
Randomized Controlled TrialChronic Pain

Research Trends of Acupuncture Therapy for Chronic Pain-Related Depression or Anxiety from 2003 to 2023: A Bibliometric Analysis.

Research on acupuncture for chronic pain-related depression and anxiety has increased over the past 20 years, with rando…

Journal of pain researchRead More →

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We scan PubMed and major integrative medicine journals every Monday and surface the highest-quality new evidence.

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