Evidence-based studies and clinical research on acupuncture efficacy
Acupuncture inhibits mast cell degranulation and modulates inflammatory pathways by suppressing NF-κB, MAPK, and TLR4/My…
Acupuncture regulates neuroinflammation through TRPV1 channel-mediated calcium influx in the brain, offering a mechanist…
Linaclotide 290 mcg daily was most effective for improving abdominal pain and bowel movement frequency in IBS-C, but hig…
Autonomic nervous system imbalance in COPD, characterized by parasympathetic hyperactivity and sympathetic suppression, …
Acupuncture significantly improved quality of life and reduced depression symptoms in IBS patients, with an 18% higher o…
Acupoint application therapy at Shenque (CV8) combined with probiotics achieved an 88.1% effectiveness rate for IBS-D co…
Acupuncture showed large effect sizes for reducing ADHD symptoms in children and adolescents, but the evidence certainty…
Acupuncture achieved a 57.9% composite response rate for IBS-D symptoms compared to 41.4% with sham treatment, with bene…
Primary myelofibrosis progression is driven by three interconnected inflammatory mechanisms—excessive cytokine productio…
GERD involves a stress-induced "neuroimmune loop" where central nervous system hypersensitivity, HPA axis activation wit…
Manual acupuncture at ST36 improved pain sensitivity and stool quality in IBS-D model rats by restoring normal fatty aci…
IBS shows significant genetic associations with structural brain changes in five cortical regions, including increased s…
We scan PubMed and major integrative medicine journals every Monday and surface the highest-quality new evidence.