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Acupuncture Research Library

Evidence-based studies and clinical research on acupuncture efficacy

Randomized Controlled TrialMigraines

Acupuncture for Migraine Without Aura and Connection-Based Efficacy Prediction: A Randomized Clinical Trial.

Real acupuncture significantly reduced monthly migraine days compared to sham acupuncture, and baseline brain connectivi…

JAMA network openRead More →
Randomized Controlled TrialMigraines

Traditional Chinese medicine versus flunarizine for the preventive treatment of episodic migraine: a randomized controlled clinical trial.

Traditional Chinese medicine (acupuncture plus herbal medicine) reduced monthly migraine days significantly more than fl…

QJM : monthly journal of t…Read More →
Research StudyMigraines

Peripheral innate immune signature links migraine and depression: Identification of PTX3 and HP as shared diagnostic biomarkers.

PTX3 and haptoglobin were identified as blood-based biomarkers capturing a shared innate immune signature between migrai…

Journal of affective disor…Read More →
Meta-AnalysisMigraines

The relationship between lifestyle behaviors and tension-type headache and migraine: A systematic review and meta-analysis.

No significant associations were found between lifestyle behaviors including alcohol consumption, BMI, smoking, and phys…

MedicineRead More →
Randomized Controlled TrialMigraines

Efficacy of acupuncture for chronic migraine: a protocol for a multicenter randomized controlled trial.

This is a protocol for a multicenter randomized controlled trial that will evaluate whether acupuncture reduces monthly …

Frontiers in neurologyRead More →
Research StudyMigraines

From trigeminal ganglion to cortex: ATG7 emerges as a key integrator of migraine pathways via multi-omics profiling.

ATG7 emerged as a key hub gene promoting autophagic flux activation in both cortical astrocytes and neurons, revealing a…

The journal of headache an…Read More →
Research StudyMigraines

Acupuncture Upregulates hsa-miR-550a-3-5p Targeting PECAM1 To Reduce Transendothelial Migration of Inflammatory Cells and Alleviate Migraine.

Acupuncture upregulates hsa-miR-550a-3-5p, which targets PECAM1 to reduce inflammatory cell migration across endothelial…

Journal of molecular neuro…Read More →
Research StudyMigraines

Functional Brain Connectivity Patterns of Headache-Mental Disorder Comorbidity in Patients With Migraine.

Specific brain connectivity patterns between subcortical nuclei and occipital/temporal cortex were identified that corre…

CNS neuroscience & the…Read More →
Research StudyMigraines

The 200 most influential publications in migraine research: a bibliometric mapping of the intellectual landscape.

The most influential migraine research emphasizes treatment approaches, CGRP pathways, and increasingly recognizes the b…

Frontiers in neurologyRead More →
Research StudyMigraines

Abnormal functional integration and effective connectivity in striatal-cortical networks with neurotransmitter system correlates in migraine without aura: A resting-state fMRI study.

Migraine without aura patients show disrupted bidirectional connectivity between subcortical structures (putamen, caudat…

Brain research bulletinRead More →
Research StudyMigraines

Mechanistic approach and therapeutic strategies in menstrual and non-menstrual migraine.

Women under 45 experience significantly more frequent and severe migraines than men, with 22% affected by menstrual migr…

Future science OARead More →
Meta-AnalysisMigraines

Acupuncture improves migraine and quality of life in patients with migraine: a systematic review with meta-analysis.

Acupuncture significantly reduced migraine duration by 4.36 hours, decreased migraine attacks and migraine days per mont…

Systematic reviewsRead More →

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We scan PubMed and major integrative medicine journals every Monday and surface the highest-quality new evidence.

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