Key Finding
This correction notice updates the methodology of a randomized controlled trial protocol studying opposing needling for knee osteoarthritis, but does not report clinical outcomes.
This publication is a correction notice for a previously published research protocol, meaning it does not contain new study results. The original study protocol describes a planned clinical trial investigating "opposing needling" - a specific acupuncture technique - for treating knee osteoarthritis. Knee osteoarthritis is a common joint condition that causes pain, stiffness, and reduced mobility, particularly affecting older adults. The correction indicates that improvements have been made to the original study design to ensure better research quality. The actual clinical trial is designed to test whether this particular acupuncture needling method can effectively reduce knee pain and improve function in people with osteoarthritis. The study will be a randomized controlled trial, which is considered the gold standard in medical research for determining whether a treatment truly works. Once the trial is completed and results are published, patients and practitioners will have better evidence about whether opposing needling is an effective treatment option for knee osteoarthritis. Until then, this correction simply ensures the research will be conducted with the most rigorous methodology possible. Patients interested in acupuncture for knee osteoarthritis should consult with a licensed acupuncturist or qualified practitioner to discuss current treatment options based on existing evidence.
This is a correction notice for a previously published randomized controlled trial protocol examining opposing needling (a traditional acupuncture technique) for knee osteoarthritis treatment. The correction does not present clinical results but indicates methodological improvements to the original study design published in Frontiers in Medicine. The trial protocol aims to evaluate the efficacy of opposing needling compared to control interventions in patients with knee osteoarthritis. Specific details regarding sample size, outcome measures, intervention parameters, and statistical analysis plans would be found in the original and corrected protocol papers. As this is a protocol correction rather than a results publication, no effect sizes or clinical outcomes are available. Clinicians should await the completed trial results before incorporating findings into clinical practice. The correction suggests enhanced rigor in the study methodology, which should improve the reliability of forthcoming results regarding this traditional acupuncture technique for knee osteoarthritis management.
Browse our directory of verified licensed practitioners near you.
Find a practitioner →📌 Modified acupuncture techniques, including electroacupuncture and needle-knife therapy, significantly reduced TNF-α levels in knee osteoarthritis patients compared to traditional acupuncture (SMD = -1.63, p < 0.01), with moderate GRADE evidence supporting this effect.
📌 The Bushen Tongdu external treatment combining full-channel moxibustion and acupoint catgut embedding achieved a 90.6% effective rate in kidney-yang deficiency type ankylosing spondylitis, significantly outperforming salazosulfapyridine on BASDAI scores and serum inflammatory markers IL-6, TNF-α, and MMP-3.
📌 Acupuncture, particularly as adjunct therapy, significantly reduced pain, morning stiffness, and key inflammatory markers including CRP, ESR, and pro-inflammatory cytokines in patients with ankylosing spondylitis across 52 randomized controlled trials.