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Combined Acupoint Massage and Abdominal Mirabilite Application for Accelerating Gastrointestinal Recovery in Pediatric Patients After Endoscopic Retrograde Cholangiopancreatography: Protocol for a Randomized Controlled Trial.

JMIR research protocols·February 2026·Xiaowei Pu, Shan Wang, Chen Cui et al.
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Key Finding

A randomized controlled trial is underway testing whether acupoint massage at ST-36, ST-25, CV-12, and PC-6 combined with abdominal mirabilite application can accelerate the return of gastrointestinal function in children aged 2–12 following ERCP, with results expected in late 2026.

What This Means For You

After certain digestive procedures, children often struggle with getting their gut moving again. A new study is exploring whether ancient healing techniques can help speed up recovery for kids who've had a procedure called ERCP — a specialized scope procedure used to treat problems with the liver, gallbladder, and pancreas in children.

ERCP is an important tool for managing serious digestive conditions in children, but it commonly causes temporary digestive slowdown afterward. This means kids may experience delayed passing of gas or having a bowel movement, which can extend their hospital stay and raise the risk of complications. Doctors are looking for safe, drug-free ways to help these young patients recover faster.

Researchers are running a carefully designed clinical trial testing two traditional Chinese medicine techniques: acupoint massage and abdominal mirabilite application. Acupoint massage involves gently stimulating specific points on the body — including points on the stomach, forearm, and leg — for two minutes each, twice a day. Mirabilite is a naturally occurring mineral salt applied to the abdomen to help stimulate digestive activity. The study is testing each approach separately and together to see which works best.

Seventy-two children between the ages of 2 and 12 are being enrolled and divided into four groups: acupoint massage only, mirabilite only, both treatments combined, or standard care alone. The main goal is to measure how quickly children pass gas and have a bowel movement after the procedure. Researchers are also tracking nausea, vomiting, and inflammation markers.

This is the first rigorous study of its kind in children after ERCP. Results are expected in late 2026 and could offer a safe, gentle recovery protocol for a vulnerable group of young patients.

If you're interested in acupuncture or acupoint therapy for your child, speak with a licensed practitioner experienced in pediatric traditional Chinese medicine.

Clinical Notes for Practitioners

This registered RCT (ITMCTR2025000670) is evaluating the individual and combined efficacy of acupoint massage and abdominal mirabilite application for accelerating postoperative gastrointestinal recovery in pediatric ERCP patients. The single-center, single-blind trial enrolls 72 children aged 2–12 years, randomized into four arms: acupoint massage (ST-36, ST-25, CV-12, PC-6; 2 min/point, twice daily), mirabilite abdominal application (1 hour, twice daily), combination therapy, or conventional care. Primary outcomes are time to first postoperative flatus and defecation. Secondary outcomes include PONV frequency and inflammatory markers. Analysis will use ITT methodology with ANOVA, chi-square, and nonparametric tests. As of January 2026, 38 participants have been enrolled. This is the first rigorous trial assessing synergistic effects of these modalities post-pediatric ERCP. Clinical takeaway: if efficacy is confirmed, this protocol could offer a standardized, nonpharmacological adjunct to reduce ileus duration and hospital stay in a high-risk pediatric population.

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