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[Clinical efficacy of intranasal acupuncture in the treatment of allergic rhinitis: a Meta-analysis].

Zhen ci yan jiu = Acupuncture research·December 2025·Ye-Ling Zhang, Wei-Xi Sun, Yan-Ru Peng et al.
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Key Finding

Intranasal acupuncture demonstrated superior efficacy compared to conventional Western medicine and external acupuncture in reducing nasal symptom severity and improving quality of life in allergic rhinitis patients across multiple validated outcome measures.

What This Means For You

Researchers analyzed 19 studies involving 1,482 people to evaluate whether intranasal acupuncture—needling performed inside the nose—helps treat allergic rhinitis (hay fever). They compared this technique to conventional Western medications and acupuncture performed on points outside the nose. The results showed that intranasal acupuncture provided better relief from nasal symptoms like congestion, sneezing, and runny nose compared to both medication and external acupuncture. Patients who received intranasal acupuncture also experienced better quality of life improvements, measured through standardized questionnaires about how allergies affected their daily activities. Laboratory testing revealed that intranasal acupuncture significantly reduced levels of IgE and IL-4, two immune system markers associated with allergic reactions. The most common side effects were mild nosebleeds and localized pain at the needle sites, which were generally well-tolerated. While these findings are encouraging for people seeking alternatives to allergy medications, the researchers noted important limitations. Most studies had small numbers of participants, and the research methods varied considerably between studies, making it difficult to draw definitive conclusions. The authors emphasized that larger, more rigorously designed clinical trials are needed to confirm these benefits and establish intranasal acupuncture as a reliable treatment option for allergic rhinitis. If you're considering this treatment approach for your allergies, consult with a licensed acupuncturist experienced in intranasal techniques to discuss whether it's appropriate for your specific situation.

Clinical Notes for Practitioners

This meta-analysis of 19 RCTs (n=1,482) evaluated intranasal acupuncture for allergic rhinitis compared to conventional Western medicine and nasal-external acupuncture. Results demonstrated statistically significant improvements favoring intranasal acupuncture across multiple outcome measures: TNSS (MD=-1.67, 95% CI -2.30 to -1.04, P<0.00001), RQLQ (MD=-3.14, 95% CI -4.16 to -2.12, P<0.00001), and TNNSS (MD=-0.52, 95% CI -0.67 to -0.36, P<0.00001). Laboratory markers showed significant reductions in serum IgE (SMD=-1.17, P=0.00001) and IL-4 (SMD=-1.14, P=0.0006). Adverse events were limited to mild epistaxis and localized pain. The authors note substantial heterogeneity across studies, small sample sizes, and limited methodological rigor as significant limitations. Clinical implications suggest intranasal acupuncture may offer superior symptomatic relief and quality of life improvements for AR patients, though higher-quality evidence from large-scale, multicenter RCTs is needed before definitive clinical recommendations can be made.

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